Our research articles

2026

Mid-infrared microscopy for label-free digital staining: initial clinical assessment
L. Duraffourg, H. Borges, M. Fernandes, M. Beurrier-Bousquet, J. Baraillon, B. Taurel, J. Le Galudec, K. Vianey, C. Maisin, L. Samaison, F. Staroz, M. Dupoy (2026).
doi: 10.3389/fbioe.2026.1774279

2026

Multi-class semantic segmentation of oral cancer tissues on whole-slide images: A SuperPixel enhanced deep learning approach
Fabian León, Anne Champagnac, Mathieu Dupoy, Jean-Michel Fayette, Tamás Dániel Csűry, Laurent Duraffourg, Pierre Saintigny (2026). doi: 10.1016/j.jpi.2026.100699

2026

Mid-infrared quantitative phase imaging in aqueous media

Marine Beurrier-Bousquet, Mathieu Dupoy, Laurent Frey, and Irène Wang (2026). Optics Express. doi: 10.1364/OE.588180

2026

Multispectral Infrared Colony Phenotyping for High-Throughput Microbiological Control of Waters

Joël Le Galudec, Mathieu Dupoy, Boris Taurel, Joris Baraillon, Pierre R. Marcoux, Laurent Duraffourg (2026). Journal of Biophotonics Volume 19, Issue 3. doi: 10.1002/jbio.70252

2025

An Introduction to Artificial Intelligence in Medicine and Its Role in Oral Potentially Malignant Disorders (OPMD)

León, F., Al Chanti, D., Champagnac, A., Dupoy, M., Caplier, A., Duraffourg, L., and Saintigny, P. (2025). In Critical Issues in Head and Neck Oncology: Key Concepts from the Ninth THNO Meeting. doi: 10.1007/978-3-031-84539-0_2

2025

Microbial Identification Through Multispectral Infrared Imaging of Colonies: A New Type of Morpho‐Spectral Fingerprinting

Joel Le Galudec, Mathieu Dupoy, Laurent Duraffourg, Véronique Rebuffel, Pierre R. Marcoux (2025). Microbial Biotechnology Volume 18, Issue 2, e70093. doi: 10.1111/1751-7915.70093

2023

Imagerie holographique numérique dans l’infrarouge moyen en milieu aqueux

Marine Beurrier-Bousquet (2023). Thèse de doctorat, Université Grenoble Alpes. https://theses.fr/2023GRALT082

2022

Imagerie hyperspectrale infrarouge pour l’identification sans marquage de pathogènes sur milieu gélosé
Le Galudec, Joël. (2022). These de doctorat, Université Grenoble Alpes. https://theses.fr/2022GRALS006

2021

MID infrared multispectral imaging for tumor tissue detection
Mathieu, G., Dupoy, M., Bonnet, S., Rebuffel, V., Coll, J.-L., & Henry, M. (2021). Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX, 11647, 126‑132. SPIE. doi: 10.1117/12.2577221

2021

Multispectral lensless imaging in the mid-infrared for label-free identification of Staphylococcus species
Le Galudec, Joel, Dupoy, M., & Marcoux, P. (2021). Label-free Biomedical Imaging and Sensing (LBIS) 2021, 11655, 116551E. SPIE. doi: https://doi.org/10.1117/12.2578264

2020

Mid-infrared multispectral lensless imaging for wide-field and label-free microbial identification
Le Galudec, J. L., Dupoy, M., Rebuffel, V., & Marcoux, P. R. (2020). Biomedical Spectroscopy, Microscopy, and Imaging, 11359, 70‑76. SPIE. doi: 10.1117/12.2557502

Technical background​

2020

Enabling low cost QCL by large scale fabrication on CMOS pilot line

Coutard, J. G., Brun, M., Fournier, M., … Duraffourg, L. (2020a). Quantum Sensing and Nano Electronics and Photonics XVII, 11288, 47‑53. SPIE. doi: 10.1117/12.2543693

2020

Volume Fabrication of Quantum Cascade Lasers on 200 mm-CMOS pilot line

Coutard, J. G., Brun, M., Fournier, M., Lartigue, O., Fedeli, F., Maisons, G., … Duraffourg, L. (2020b). Scientific Reports, 10(1), 6185. doi: 10.1038/s41598-020-63106-4

2020

Miniaturization of mid-IR sensors on Si : Challenges and perspectives

Nicoletti, S., Fédéli, J.-M., Fournier, M., Labeye, P., Barritault, P., Marchant, A., … Duraffourg, L. (2019). Silicon Photonics XIV, 10923, 37‑46. SPIE. doi: 10.1117/12.2506759

Research programs

ATHENA

ATHENA is an European project funded by the Chips-JU initiative. It aims at strengthening European economy in high-tech imaging technologies, by preparing more advanced microbolometers manufacturing [read more].

MILADO

The MILADO project aims to revolutionize mid-infrared (MIR) laser technology by developing cost-effective, high-volume manufacturing processes for Quantum Cascade Lasers (QCLs). These lasers are essential for various spectroscopic applications due to their… [read more]